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Contraindicated (1)pentobarbital will lower the extent or effect of lumefantrine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with powerful CYP3A4 inducers may result in reduced serum concentrations and loss of antimalarial efficacypentobarbital will reduce the level or effect of eltrombopag by impacti